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Interested in experimental ultrasound imaging, microfluidics, and fluid dynamics? Join our research program on molecular ultrasound imaging using functionalized, monodisperse microbubbles. The project addresses a fundamental question: how does the acoustic response of a microbubble change when it binds to a molecular target on a blood vessel wall? By combining monodisperse designer microbubbles, microfluidic blood vessel models, and programmable ultrasound imaging, you will investigate how binding alters the acoustic signature of individual bubbles and how this effect can be exploited to acoustically distinguish bound from freely circulating microbubbles.
Beyond ultrasound imaging, there is ample opportunity to develop complementary experimental approaches to understand the underlying bubble physics. These include ultra-high-speed imaging of bubble dynamics at up to ten million frames per second and laser-induced fluorescence imaging to probe microbubble behavior and shell dynamics. The goal is to obtain a full physical understanding of the mechanisms governing the acoustic response of bound microbubbles.
You will perform ultrasound imaging experiments using a fully programmable Verasonics NXT research ultrasound system to study microbubbles flowing through and binding to microfluidic channels in hydrogel-based blood vessel models. Using the acquired RF data, you will track microbubbles as they travel through the vessel phantom and bind to the vessel wall, and analyze changes in echo amplitude and spectral content associated with binding.
You will work closely with three PhD students who develop the microbubbles and tune their molecular targeting and viscoelastic shell properties. You will have substantial freedom to develop new experimental approaches and imaging strategies, and there is ample opportunity to initiate and coordinate experiments together with the PhD students while contributing to their supervision alongside your own research track.
Your profile- A PhD degree in Applied Physics, Electrical Engineering, Biomedical Engineering, Mechanical Engineering, or a closely related field.
- Experience with ultrasound imaging and strong programming skills in Matlab.
- Strong experimental skills and creativity in experimental design.
- Experience with microfluidics, fluid mechanics, or high-speed imaging is a plus.
- Interest in interdisciplinary research combining fluid dynamics, interfacial physics, acoustics, and microfluidics.
- Good communication and writing skills in English.
- A full-time position for 1 year (which can be extended after a good evaluation)
- The salary and associated conditions are in accordance with the collective labour agreement for Dutch universities (CAO-NU).
- You will receive a gross monthly salary ranging from € 3.546,- to € 5.538,-.
- There are excellent benefits, including a holiday allowance of 8% of the gross annual salary, an end-of-year bonus of 8.3%, and a solid pension scheme.
- A minimum of 232 leave hours in case of full-time employment based on a formal workweek of 38 hours. A full-time employment in practice means 40 hours a week, therefore resulting in 96 extra leave hours on an annual basis.
- Free access to sports facilities on campus.
- A family-friendly institution that offers parental leave (both paid and unpaid).
- Excellent career support and courses for your professional and personal development.
Are you interested in this position? Please send your application via the 'Apply now' button below beforeApril 18, 2026,and include:
- A cover letter explaining your specific interest and outlining your prior experience on the research topic
- List of publications
- Name and email addresses of at least two visible references who are willing to send a recommendation letter on your behalf.
An interview with a scientific presentation on your previous work will be part of the interview process.
For more information regarding this position, you are welcome to contact: t.j.segers@utwente.nl.
Screening is part of the selection process.
About the departmentYou will be embedded in the BIOS/Lab on a Chip group at the University of Twente, part of the Max Planck Center Twente for Complex Fluid Dynamics, the J.M. Burgers Research Center for Fluid Mechanics, and the MESA+ Institute for Nanotechnology. You will work in a multidisciplinary research environment with strong interactions between microfluidics, acoustics, and biomedical engineering.
About the organisationThe faculty of Electrical Engineering, Mathematics and Computer Science (EEMCS) uses mathematics, electronics and computer technology to contribute to the development of Information and Communication Technology (ICT). With ICT present in almost every device and product we use nowadays, we embrace our role as contributors to a broad range of societal activities and as pioneers of tomorrow's digital society. As part of atech university that aims to shape society, individuals and connections, our faculty works together intensively with industrial partners and researchers in the Netherlands and abroad, and conducts extensive research for external commissioning parties and funders. Our research has a high profile both in the Netherlands and internationally. It has been accommodated in three multidisciplinary UT research institutes: Mesa+ Institute, TechMed Centre and Digital Society Institute.
Job detailsTitle
Postdoc position in Ultrasound Imaging and Microbubble Physics
Published
2025-12-18
#J-18808-Ljbffr€3546 - €5538 monthly