Would you like to monitor the activity of single mechanosensitive membrane channels being inserted into artificial cell membranes? This will be the focus of a PhD project that will use biophysical tools combined with cell?'free protein synthesis. A microfluidics system with freestanding lipid bilayers will enable the electrical monitoring of ion channels while a mechanical load is directly applied. The knowledge generated by this project will contribute to making synthetic cells which are responsive to the environment. The general goal is to advance (mechano)sensing in synthetic cells through optimization of ion channels incorporation and activity in lipid bilayers. The project sits at the interface of biophysics, engineering and biochemistry. The PhD student will be part of an interdisciplinary very active consortium called EVOLF.
Job requirements- Qualified candidates have a Master in physics, chemistry, engineering, or a related field.
- Successful candidates are motivated by a deep scientific curiosity, have excellent experimental and quantitative skills and possess a drive to learn and to develop new methods and concepts.
PLEASE NOTE: The applications will be reviewed as soon as they are received, therefore it is preferable to submit your application as soon as it is ready.
TU Delft (Delft University of Technology)Delft University of Technology is built on strong foundations. As creators of the world?'famous Dutch waterworks and pioneers in biotech, TU Delft is a top international university combining science, engineering and design. It delivers world class results in education, research and innovation to address challenges in the areas of energy, climate, mobility, health and digital society. For generations, our engineers have proven to be entrepreneurial problem?'solvers, both in business and in a social context.
At TU Delft we embrace diversity as one of our core values and we actively engage to be a university where you feel at home and can flourish. We value different perspectives and qualities. We believe this makes our work more innovative, the TU Delft community more vibrant and the world more just. Together, we imagine, invent and create solutions using technology to have a positive impact on a global scale. That is why we invite you to apply. Your application will receive fair consideration.
Challenge. Change. Impact!
Faculty Applied SciencesWith more than 1,100 employees, including 150 pioneering principal investigators, as well as a population of about 3,600 passionate students, the Faculty of Applied Sciences is an inspiring scientific ecosystem. Focusing on key enabling technologies, such as quantum?' and nanotechnology, photonics, biotechnology, synthetic biology and materials for energy storage and conversion, our faculty aims to provide solutions to important problems of the 21st century. To that end, we educate innovative students in broad Bachelor's and specialist Master's programmes with a strong research component. Our scientists conduct ground?'breaking fundamental and applied research in the fields of Life and Health Science & Technology, Nanoscience, Chemical Engineering, Radiation Science & Technology, and Engineering Physics. We are also training the next generation of high school teachers.
here to go to the website of the Faculty of Applied Sciences.
Conditions of employmentDoctoral candidates will be offered a 4?'year period of employment in principle, but in the form of 2 employment contracts. An initial 1,5 year contract with an official go/no go progress assessment within 15 months. Followed by an additional contract for the remaining 2,5 years assuming everything goes well and performance requirements are met.
Salary and benefits are in accordance with the Collective Labour Agreement for Dutch Universities, increasing from € 3059 per month in the first year to € 3881 in the fourth year. As a PhD candidate you will be enrolled in the TU Delft Graduate School. The TU Delft Graduate School provides an inspiring research environment with an excellent team of supervisors, academic staff and a mentor. The Doctoral Education Programme is aimed at developing your transferable, discipline?'related and research skills.
The TU Delft offers a customisable compensation package, discounts on health insurance, and a monthly work costs contribution. Flexible work schedules can be arranged.
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Additional information Application procedureAre you interested in this vacancy? Please apply no later than 13 October 2025 via the application button and upload the following documents:
- Motivation letter,
- CV,
- And grade reports from your bachelor and master studies.
Doing a PhD at TU Delft requires English proficiency at a certain level to ensure that the candidate is able to communicate and interact well, participate in English?'taught Doctoral Education courses, and write scientific articles and a final thesis. For more details please check the Graduate Schools Admission Requirements.
Please note- You can apply online. We will not process applications sent by email and/or post.
- A pre?'employment screening can be part of the selection procedure.
- For the final candidates, a knowledge security check will be part of the application procedure. For more information on this check, please consult Chapter 8 of the National Knowledge Security Guidelines. We carry out this check on the basis of legitimate interest.
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