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Head of Molecular Design & Engineering (m/w/d)

Bayer is a global enterprise with core competencies in the Life Science fields of health care and agriculture. Its products and services are designed to benefit people and improve their quality of life. At Bayer you have the opportunity to be part of a culture where we value the passion of our employees to innovate and give them the power to change.

Head of Molecular Design & Engineering (m/w/d)


  • Plan and lead internal lead discovery and optimization campaigns for antibodies and new modalities, including bispecific and multispecific antibodies or other targeted proteins, at Bayer’s “Biologics Research” center for antibody discovery and protein engineering in Wuppertal, Germany
  • Continuously ensure our exploitation of state-of-the-art platforms for antibody/biologics lead discovery and lead optimization, both internally and with external collaboration partners
  • Coordinate and supervise a molecular biology research with several research technicians
  • Closely collaborate with an extensive network of international scientists within the department and across Bayer to drive our portfolio of product-oriented research programs
  • Use your expert knowledge of biologics approaches, drug discovery, and the biologics industry to represent Biologics Research on cross-disciplinary teams who propose, manage, and drive internal therapeutic research projects or external collaborations
  • Play an active role in proposing and evaluating new therapeutic target opportunities or biologic modality opportunities and play an expert role for the committees that manage and shape our Biologics portfolios


  • PhD in biochemistry, molecular biology or comparable combined with a long-term professional working experience in a relavant field
  • Demonstrated productivity as well as professional experience in biotech/biopharmaceutical industry environment
  • In-depth and hands-on knowledge of state-of-the-art HTS molecular biology cloning technologies
  • Experience/background in the generation of high complexity protein libraries (antibodies and enzymes)
  • Strong understanding of antibody engineering including re-formatting, germlining, affinity and functional optimization, PTM corrections and humanization, also covering antibody derived formats like e.g., Fabs, scFv, VHH and BsAb
  • Proficiency in data and workflow management as well as software systems for biologics R&D
  • Strong leadership skills, along with a high level of assertiveness and an excellent interpersonal and teamwork approach, as well as outstanding analytical thinking
  • Ideally broad experience in biotherapeutics research in a (biologics) drug discovery environment, including a strong working knowledge of disease biology
  • Effective presentation and communications skills and fluent command of English, both verbal and written


Are you looking for a new challenge where you can show your passion for innovation? Are you interested in working as part of a global team to improve people’s lives? Then send us your online application including cover letter, CV and references.

Bayer welcomes applications from all individuals, regardless of race, national origin, gender, age, physical characteristics, social origin, disability, union membership, religion, family status, pregnancy, sexual orientation, gender identity, gender expression or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.

Location: ​​ ​ Wuppertal-Aprath​

​​Division: ​ Pharmaceuticals​

Reference Code: 422241​

Art des Stellenangebotes:


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