Exciting Opportunity: Principal Scientist MSAT
Are you an experienced bioprocessing/MSAT scientist looking to work at the interface of development and manufacturing? This organisation is seeking a Principal Scientist (MSAT) to lead complex biologics projects, support process scale-up, and drive successful delivery into GMP manufacturing environments.
Job Title: Principal Scientist MSAT
Vacancy Type: Permanent
Location: North East England
Salary: £49,045 - £69,045
About the Organisation
You’ll be joining an established organisation supporting the development and manufacture of advanced pharmaceutical products. The business collaborates with partners across the product lifecycle, from early‑stage development through to GMP manufacturing, with a focus on delivering high‑quality, scalable processes.
The MSAT (Manufacturing Science & Technology) team plays a key role in bridging development and manufacturing, ensuring processes are robust, transferable, and suitable for commercial production of complex biologics. The environment is highly collaborative, offering strong technical ownership and exposure to multidisciplinary project teams.
The Role of the Principal Scientist – MSAT
In this role, you will act as a technical lead on complex programmes, supporting the transfer and scale‑up of bioprocesses into GMP manufacture. You’ll combine strong scientific expertise with project delivery, ensuring processes are implemented effectively and meet quality and regulatory expectations.
Key responsibilities include:
- Leading process transfer and scale‑up activities into GMP manufacturing environments, being the SME within biologics
- Preparing and reviewing technical documentation, including process descriptions, change controls, and risk assessments
- Planning and overseeing experimental and pilot‑scale studies, with responsibility for data interpretation and reporting
- Ensuring processes are robust, scalable, and suitable for manufacturing operations
- Working cross‑functionally with operations, quality, engineering, and supply chain teams
- Supporting investigations, including deviations, root cause analysis, and impact assessments
The Ideal Candidate for the Principal/Senior Scientist – MSAT Role
To succeed in this role, you will need:
- A degree (or higher) in a scientific or engineering discipline, with strong, recent industry experience
- Proven, recent expertise in bioprocessing, including upstream and/or downstream operations
- Recent exposure to process transfer, MSAT, or manufacturing support environments
- Recent experience within biologics or advanced therapeutic development
- Experience working within a GMP environment, ideally supporting manufacturing or scale‑up activities
- Demonstrated ability to lead or contribute to complex technical projects
- Strong problem‑solving skills and data interpretation capability
- Excellent communication skills and experience working across multidisciplinary teams
- Previous mentoring or informal leadership experience
Why This Role?
This is a great opportunity for a scientist looking to step into a more senior, technically influential position. You’ll work on high‑impact projects, gain exposure to manufacturing environments, and play a key role in bringing processes from development into real‑world production.
SRG are the UK’s number one recruitment company specialising in the science, engineering, clinical, pharmaceutical, food/FMCG, renewable, biotech, chemicals and medical devices sectors.
As scientists ourselves, our specialist sector knowledge and passion are second to none. We’re committed to providing outstanding career opportunities at all levels.
If this role isn’t quite right for you, feel free to get in touch or visit www.srgtalent.com to explore other opportunities.