Proclinical is working alongside a leading global pharmaceutical organisation is seeking an experienced Materials Characterisation & Formulation Scientist to support drug product development, material change assessments, and manufacturing process performance prediction activities.
This is an excellent opportunity for a pharmaceutical scientist with expertise in oral solid dosage forms (OSD), formulation development, process development, manufacturing science, material characterisation, and pharmaceutical manufacturing operations.
You will play a key role in understanding how raw material, excipient, and API variability can impact product quality, manufacturability, and process robustness, using a combination of laboratory experimentation, process understanding, and scientific data analysis.
Key Responsibilities
Design and execute formulation and process development studies.
Evaluate the impact of API and excipient variability on manufacturing performance and product quality.
Assess supplier changes and material variability through laboratory experimentation and risk assessment activities.
Develop representative small-scale models of pharmaceutical manufacturing processes.
Investigate relationships between material attributes, process parameters, and critical quality attributes (CQAs).
Conduct studies involving:
Powder blending
Content uniformity
Wet granulation
Dry granulation
Powder flow and feeding behaviour
Tablet compression
Compaction analysis
Tablet sticking investigations
Film coating
Stability and robustness assessments
Support process understanding, scale-up activities, and manufacturability assessments.
Analyse experimental data and provide scientific recommendations.
Prepare technical reports, presentations, and project updates.
Collaborate with multidisciplinary teams including formulation, process, analytical, and manufacturing scientists.
Skills & Experience Required
Degree in Pharmaceutical Sciences, Pharmaceutics, Chemistry, Chemical Engineering, Materials Science, or a related discipline.
Proven years' experience within pharmaceutical development, pharmaceutical manufacturing, MSAT, process development, or formulation development environments.
Strong knowledge of oral solid dosage forms (OSD) including tablets and capsules.
Experience with pharmaceutical manufacturing unit operations including:
Blending
Granulation
Compression
Film coating
Understanding of material attributes and their impact on product and process performance.
Experience designing experimental studies and interpreting scientific data.
Knowledge of process robustness, scale-up principles, and manufacturing performance assessment.
Strong technical writing and scientific reporting experience.
Excellent problem-solving and stakeholder communication skills.
Highly Desirable
Experience supporting technology transfer, scale-up, or commercial manufacturing.
Knowledge of statistical analysis, Design of Experiments (DoE), process modelling, simulation tools, or predictive modelling.
Experience investigating manufacturing challenges and process performance issues.
Familiarity with material characterisation techniques and risk-based decision making.
What's on Offer?
Opportunity to join a highly respected global pharmaceutical organisation.
Complex and scientifically challenging development projects.
Exposure to commercial manufacturing and product lifecycle activities.
Collaborative multidisciplinary environment.
Long-term 18-month contract opportunity.
Apply today to discuss this Pharmaceutical Formulation Scientist opportunity in confidence.
If you are having difficulty in applying or if you have any questions, please contact Neil Walton at (url removed).
If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists please request a call back at the top of this page.
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Salary description
£35000.00 - £40000.00 per year