LCMS Specialist

Exciting Opportunity: LC‑MS Specialist

Are you an experienced LC‑MS scientist who enjoys being the go‑to expert for keeping instruments running at their best? This organisation is seeking an LC‑MS Specialist to take ownership of a busy suite of LC‑MS systems, supporting drug discovery projects through high‑quality analytical data and robust instrument performance.

Job Title: LC‑MS Specialist
Vacancy Type: 1-2 Year Fixed‑Term Contract
Location: Cambridge
Salary: DOE

The Role of the LC‑MS Specialist

In this laboratory‑based role, you will be the technical lead for LC‑MS activities, with a strong focus on instrument reliability, method execution, and data quality. Working closely with chemistry and biology teams, you'll ensure smooth day‑to‑day operation of open‑access LC‑MS platforms while contributing analytical insight to discovery programmes.

Key responsibilities include:

Owning and managing multiple LC‑MS systems, including routine maintenance, calibration, fault‑finding, and performance monitoring
Acting as the first point of contact for LC‑MS troubleshooting and best practice
Supporting purification and analysis of chiral and achiral compounds
Generating high‑quality analytical and physchem data to support medicinal chemistry decision‑making
Promoting effective use of LC‑MS across cross‑functional project teams
Supporting safe and compliant laboratory operations on a daily basisWhile exposure to DMPK or in vitro ADME work is beneficial, the core requirement for this role is strong hands‑on LC‑MS expertise and instrument ownership.

The Ideal Candidate for the LC‑MS Specialist Role

To succeed in this position, you will bring:

A degree in chemistry or a related scientific discipline
At least 3 years' recent practical, hands‑on experience working with LC‑MS systems
Proven, recent experience maintaining, calibrating, and troubleshooting LC‑MS instrumentation
Confidence supporting open‑access LC‑MS environments
Strong analytical thinking, attention to detail, and data interpretation skills
Excellent communication skills and the ability to work confidently with interdisciplinary teamsDesirable experience includes:

Hands‑on use of Shimadzu and/or Agilent LC‑MS platforms
Experience with high‑resolution mass spectrometry or SFC
Exposure to physchem or in vitro ADME assays (not essential).

Why This Role?

This is a fantastic opportunity for someone who enjoys being the technical backbone of an analytical lab - ensuring LC‑MS systems perform reliably, supporting multiple discovery programmes, and working in a collaborative, science‑driven environment with excellent training and development opportunities.

For more information, please contact Selby De Klerk at SRG

SRG are the UK's number one recruitment company specialising in the science, engineering, clinical, pharmaceutical, food/FMCG, renewable, biotech, chemicals and medical devices sectors.
As scientists ourselves, our specialist sector knowledge and passion are second to none. We're committed to providing outstanding temporary, contract, and permanent career opportunities at all levels.

If this role isn't quite right for you, feel free to get in touch or visit (url removed) to view our other vacancies.

Guidant, Carbon60, Lorien & SRG - The Impellam Group Portfolio are acting as an Employment Business in relation to this vacancy