Biochemist / Structural Biologist

How do cohesin and condensin shape our DNA? How are these protein complexes regulated to enable processes like cell division and gene control? And how does the related SMC5/6 complex silence viruses? We are looking for a Biochemist / Structural Biologist to help us answer these important questions.

The group of Benjamin Rowland , within the NKI Division of Cell Biology, is looking for a biochemist / structural biologist to join their interdisciplinary team. The Rowland lab studies genome control by cohesin, condensin and SMC5/6, with the aim of discovering how these protein complexes shape the genome and determine its function.

In this role, you will contribute to research that focuses on:

• Discovering how cohesin, condensin and SMC5/6 build DNA loops that organize the genome in three dimensions
• Understanding the mechanisms by which these complexes entrap and release DNA
• Studying sister chromatid cohesion and mitotic chromosome condensation
• Investigating how these complexes contribute to viral genome silencing

We are looking for an experienced biochemist and/or structural biologist who:

• Has hands‑on experience with biochemical assays and protein purification;
• Preferably has experience with Cryo‑EM and/or biophysics;
• Has a good command of English.

Applicants with degrees ranging from PhD to BSc are encouraged to apply. Your salary scale will be determined based on your level of experience.

The basis for your employment conditions is in accordance with the CLA Hospitals . You will receive from us:

• A year's contract for 36 hours per week, with the prospect of extension;
• A gross monthly salary between € 3.102,- and € 5.978,- based on a 36-hour working week, in line with FWG45, 50, 55 or 60and depending on your experience;
• 144 holiday hours and 57 hours of Personal Life Budget, with full-time employment;
• Annual holiday pay of 8.33% and a fixed end‑of‑year bonus of 8.33%;
• A travel allowance of €0.23 per km;
• Free parking at the Netherlands Cancer Institute. And with our bicycle plan and discount on public transport we also make it attractive for you to leave the car at home;
• A great opportunity in a specialised hospital where you can also continue to learn and grow yourself if you wish: the AVL Academy offers innovative and inspiring education in the field of oncology professional knowledge, skills and personal development;
• Opportunity to exercise during working hours at our Fit Boutiqs;
• An active staff association.

We are curious about your talent! Will you be the one to make a difference in the world of cancer care and research? Apply now by using the apply/solliciteer button!

Please attach your motivation letter (maximum one page), CV and contact details of two references to the application form. Make sure to include your reference information together with your application documents, as there is no option to submit them separately.

For further information about the position, please contact Judith Haarhuis (j.haarhuis@nki.nl).

This vacancy is open for applications until 31 January 2026.