Leiden Universiteit

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Originele vacaturetekst

PhD candidate

Nog 40 dagen om te solliciteren

The Faculty of Science and the Leiden Institute of Chemistry are looking for a

PhD candidate, to develop correlative light-electron microscopy approaches to image vaccine-immune cell interactions

Key responsibilities
Recent months have shown the pivotal importance of vaccines to modern healthcare, and society. Yet the way many of these vaccines interact with the immune system at a molecular level remains poorly understood. In this project, you will be working on developing new chemical biology approaches aimed at imaging these interactions. The project will involve extensive method development to use bioorthogonal vaccine analogues (made with help from dedicated postdocs), testing these in existing correlative light-electron microscopy setups, and also to push the boundaries of the imaging techniques to include tomography, super-resolution, and other exciting methodology we have available in house. For this we are looking for an enthusiastic, motivated PhD candidate, that is not afraid to try new things, and tackle multidisciplinary problems.

Selection criteria

  • Master degree in Life Science and Technology, Biomedical Science, or equivalent;
  • Proven interest in confocal, super-resolution, or other fluorescence microscopy techniques and/or proven interest in electron microscopy/tomography;
  • A solid knowledge of immunology and cell biology;
  • Proven Proficient in English;
  • Excellent communication skills.

Our organisation
The research carried out at the Faculty of Science is very diverse, ranging from mathematics, information science, astronomy, physics, chemistry and bio-pharmaceutical sciences to biology and environmental sciences. The research activities are organised in eight institutes. These institutes offer eight bachelor’s and twelve master’s programmes. The faculty has grown strongly in recent years and now has more than 2.200 staff and almost 4,200 students. We are located at the heart of Leiden’s Bio Science Park, one of Europe’s biggest science parks, where university and business life come together.

The chemistry and life science research in the Leiden Institute of Chemistry (LIC) is organized around two major research areas: ‘Chemical Biology’ and ‘Energy & Sustainability’. The institute’s research themes illustrate the central position of chemistry between biology, medicine and physics. The various research topics carried out within these themes are ideal for executing interdisciplinary research. For more information, see the website of the Faculty of Science.

Terms and conditions
We offer a full-time position for initially one year. After a positive evaluation of the progress of the thesis, personal capabilities and compatibility the appointment will be extended by a further three years. Salary rangefrom € 2.395,- to € 3.061,- gross per month (pay scale P in accordance with the Collective Labour Agreement for Dutch Universities).

Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year bonuses(8.3 %), training and career development and sabbatical leave. Our individual choices model gives you some freedom to assemble your own set of terms and conditions. Candidates from outside the Netherlands may be eligible for a substantial tax break. For more information, see the website.

All our PhD students are embedded in the Leiden University Graduate School of Science.Our graduate school offers several PhD training courses at three levels: professional courses, skills training and personal effectiveness.

LeidenUniversityis strongly committed to diversity within its community and especially welcomes applications from members of underrepresented groups.

Enquiries can be made to Sander van Kasteren, email s.i.van.kasteren@chem.leidenuniv.nl.

To apply for this vacancy, please send an email to Jessica van Krimpen, e-mail j.e.van.krimpen@lic.leidenuniv.nl. Please ensure that you upload the following additional documents quoting the vacancy number:

  • Letter of motivation addressed to Dr. Sander van Kasteren, including a statement why you are suited for this position;
  • Curriculum vitae;
  • Transcripts of bachelor and master curriculum courses, including grades;
  • Three references, including names, affiliations and email addresses .

Only applications received no later than the 15th of April can be considered.

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